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Alpha1a-Adrenoceptor Genetic Variant Triggers Vascular Smooth Muscle Cell Hyperproliferation and Agonist Induced Hypertrophy via EGFR Transactivation Pathway
α(1a) Adrenergic receptors (α(1a)ARs) are the predominant AR subtype in human vascular smooth muscle cells (SMCs). α(1a)ARs in resistance vessels are crucial in the control of blood pressure, yet the impact of naturally occurring human α(1a)AR genetic variants in cardiovascular disorders remains poo...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646490/ https://ncbi.nlm.nih.gov/pubmed/26571308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142787 |
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