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Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway

We previously identified a naturally occurring human SNP, G247R, in the third intracellular loop of the α(1a)-adrenergic receptor (α(1a)-247R) and demonstrated that constitutive expression of α(1a)-247R results in twofold increased cell proliferation compared with WT. In the present study we elucida...

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Detalhes bibliográficos
Main Authors: Oganesian, Anush, Yarov-Yarovoy, Vladimir, Parks, William C., Schwinn, Debra A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241756/
https://ncbi.nlm.nih.gov/pubmed/22089237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116271108
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