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All-Trans Retinoic Acid-Induced Deficiency of the Wnt/β-Catenin Pathway Enhances Hepatic Carcinoma Stem Cell Differentiation

Retinoic acid (RA) is an important biological signal that directly differentiates cells during embryonic development and tumorigenesis. However, the molecular mechanism of RA-mediated differentiation in hepatic cancer stem cells (hCSCs) is not well understood. In this study, we found that mRNA expre...

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Publicat a:PLoS One
Autors principals: Zhu, Xinfeng, Wang, Wenxue, Zhang, Xia, Bai, Jianhua, Chen, Gang, Li, Li, Li, Meizhang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646487/
https://ncbi.nlm.nih.gov/pubmed/26571119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143255
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