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All-Trans Retinoic Acid-Induced Deficiency of the Wnt/β-Catenin Pathway Enhances Hepatic Carcinoma Stem Cell Differentiation

Retinoic acid (RA) is an important biological signal that directly differentiates cells during embryonic development and tumorigenesis. However, the molecular mechanism of RA-mediated differentiation in hepatic cancer stem cells (hCSCs) is not well understood. In this study, we found that mRNA expre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhu, Xinfeng, Wang, Wenxue, Zhang, Xia, Bai, Jianhua, Chen, Gang, Li, Li, Li, Meizhang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646487/
https://ncbi.nlm.nih.gov/pubmed/26571119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143255
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