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All-trans retinoic acid regulates hepatic bile acid homeostasis
Retinoic acid (RA) and bile acids share common roles in regulating lipid homeostasis and insulin sensitivity. In addition, the receptor for RA (retinoid x receptor) is a permissive partner of the receptor for bile acids, farnesoid x receptor (FXR/NR1H4). Thus, RA can activate the FXR-mediated pathwa...
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| Udgivet i: | Biochem Pharmacol |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4236914/ https://ncbi.nlm.nih.gov/pubmed/25175738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.08.018 |
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