Insights into the Determination of the Templating Nucleotide at the Initiation of φ29 DNA Replication

Bacteriophage φ29 from Bacillus subtilis starts replication of its terminal protein (TP)-DNA by a protein-priming mechanism. To start replication, the DNA polymerase forms a heterodimer with a free TP that recognizes the replication origins, placed at both 5′ ends of the linear chromosome, and initi...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: del Prado, Alicia, Lázaro, José M., Longás, Elisa, Villar, Laurentino, de Vega, Miguel, Salas, Margarita
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646400/
https://ncbi.nlm.nih.gov/pubmed/26400085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.682278
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