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Histone Deacetylase 3 Coordinates Deacetylase-independent Epigenetic Silencing of Transforming Growth Factor-β1 (TGF-β1) to Orchestrate Second Heart Field Development

About two-thirds of human congenital heart disease involves second heart field-derived structures. Histone-modifying enzymes, histone deacetylases (HDACs), regulate the epigenome; however, their functions within the second heart field remain elusive. Here we demonstrate that histone deacetylase 3 (H...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Lewandowski, Sara L., Janardhan, Harish P., Trivedi, Chinmay M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646383/
https://ncbi.nlm.nih.gov/pubmed/26420484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684753
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