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Phosphorylation of Serine 402 Regulates RacGAP Protein Activity of FilGAP Protein
FilGAP is a Rho GTPase-activating protein (GAP) that specifically regulates Rac. FilGAP is phosphorylated by ROCK, and this phosphorylation stimulates its RacGAP activity. However, it is unclear how phosphorylation regulates cellular functions and localization of FilGAP. We found that non-phosphoryl...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646280/ https://ncbi.nlm.nih.gov/pubmed/26359494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.666875 |
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