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Calpain Cleaves Most Components in the Multiple Aminoacyl-tRNA Synthetase Complex and Affects Their Functions

Nine aminoacyl-tRNA synthetases (aaRSs) and three scaffold proteins form a super multiple aminoacyl-tRNA synthetase complex (MSC) in the human cytoplasm. Domains that have been added progressively to MSC components during evolution are linked by unstructured flexible peptides, producing an elongated...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Lei, Hui-Yan, Zhou, Xiao-Long, Ruan, Zhi-Rong, Sun, Wei-Cheng, Eriani, Gilbert, Wang, En-Duo
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646279/
https://ncbi.nlm.nih.gov/pubmed/26324710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681999
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