A Novel Peroxisome Proliferator-activated Receptor (PPAR)γ Agonist 2-Hydroxyethyl 5-chloro-4,5-didehydrojasmonate Exerts Anti-Inflammatory Effects in Colitis

Inflammatory bowel disease (IBD) is a chronic inflammatory disease with increasing incidence and prevalence worldwide. Here we investigated the newly synthesized jasmonate analogue 2-hydroxyethyl 5-chloro-4,5-didehydrojasmonate (J11-Cl) for its anti-inflammatory effects on intestinal inflammation. F...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Choo, Jieun, Lee, Yunna, Yan, Xin-jia, Noh, Tae Hwan, Kim, Seong Jin, Son, Sujin, Pothoulakis, Charalabos, Moon, Hyung Ryong, Jung, Jee H., Im, Eunok
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646205/
https://ncbi.nlm.nih.gov/pubmed/26342083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.673046
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