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Integrin α3β1 Binding to Fibronectin Is Dependent on the Ninth Type III Repeat

Fibronectin (Fn) is a promiscuous ligand for numerous cell adhesion receptors or integrins. The vast majority of Fn-integrin interactions are mediated through the Fn Arg-Gly-Asp (RGD) motif located within the tenth type III repeat. In the case of integrins αIIbβ3 and α5β1, the integrin binds RGD and...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Brown, Ashley C., Dysart, Marilyn M., Clarke, Kimberly C., Stabenfeldt, Sarah E., Barker, Thomas H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646199/
https://ncbi.nlm.nih.gov/pubmed/26318455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.656702
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