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Acid-dependent Interleukin-1 (IL-1) Cleavage Limits Available Pro-IL-1β for Caspase-1 Cleavage

Noncommunicable diseases such as cardiovascular disease (stroke and heart attack), cancer, chronic respiratory disease, and diabetes are a leading cause of death and disability worldwide and are worsened by inflammation. IL-1 is a driver of inflammation and implicated in many noncommunicable disease...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Principais autores: Edye, Michelle E., Brough, David, Allan, Stuart M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646186/
https://ncbi.nlm.nih.gov/pubmed/26324708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.667162
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