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Pannexin-1-dependent caspase-1 activation and secretion of IL-1β is regulated by zinc

Inflammatory processes induced by IL-1β are critical for host defence responses, but are also implicated in disease. Zinc deficiency is a common consequence of, or contributor to, human inflammatory disease. However, the molecular mechanisms through which zinc contributes to inflammatory disease rem...

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Autori principali: Brough, David, Pelegrin, Pablo, Rothwell, Nancy J
Natura: Artigo
Lingua:Inglês
Pubblicazione: WILEY-VCH Verlag 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696683/
https://ncbi.nlm.nih.gov/pubmed/19130485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838843
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