Characterization of Inhibitors and Monoclonal Antibodies That Modulate the Interaction between Plasmodium falciparum Adhesin PfRh4 with Its Erythrocyte Receptor Complement Receptor 1

Plasmodium falciparum parasites must invade red blood cells to survive within humans. Entry into red blood cells is governed by interactions between parasite adhesins and red blood cell receptors. Previously we identified that P. falciparum reticulocyte binding protein-like homologue 4 (PfRh4) binds...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Lim, Nicholas T. Y., Harder, Markus J., Kennedy, Alexander T., Lin, Clara S., Weir, Christopher, Cowman, Alan F., Call, Melissa J., Schmidt, Christoph Q., Tham, Wai-Hong
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646181/
https://ncbi.nlm.nih.gov/pubmed/26324715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.657171
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