Characterization of Inhibitors and Monoclonal Antibodies That Modulate the Interaction between Plasmodium falciparum Adhesin PfRh4 with Its Erythrocyte Receptor Complement Receptor 1

Plasmodium falciparum parasites must invade red blood cells to survive within humans. Entry into red blood cells is governed by interactions between parasite adhesins and red blood cell receptors. Previously we identified that P. falciparum reticulocyte binding protein-like homologue 4 (PfRh4) binds...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lim, Nicholas T. Y., Harder, Markus J., Kennedy, Alexander T., Lin, Clara S., Weir, Christopher, Cowman, Alan F., Call, Melissa J., Schmidt, Christoph Q., Tham, Wai-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646181/
https://ncbi.nlm.nih.gov/pubmed/26324715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.657171
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