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Histone deacetylase inhibitor‐mediated cell death is distinct from its global effect on chromatin
Romidepsin and vorinostat are histone deacetylase inhibitors (HDACis) that have activity in T‐cell lymphomas, but have not gained traction in solid tumors. To gain deeper insight into mechanisms of HDACi efficacy, we systematically surveyed 19 cell lines with different molecular phenotypes, comparin...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Oncol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646083/ https://ncbi.nlm.nih.gov/pubmed/24954856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.05.001 |
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