Sph3 Is a Glycoside Hydrolase Required for the Biosynthesis of Galactosaminogalactan in Aspergillus fumigatus

Aspergillus fumigatus is the most virulent species within the Aspergillus genus and causes invasive infections with high mortality rates. The exopolysaccharide galactosaminogalactan (GAG) contributes to the virulence of A. fumigatus. A co-regulated five-gene cluster has been identified and proposed...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Bamford, Natalie C., Snarr, Brendan D., Gravelat, Fabrice N., Little, Dustin J., Lee, Mark J., Zacharias, Caitlin A., Chabot, Josée C., Geller, Alexander M., Baptista, Stefanie D., Baker, Perrin, Robinson, Howard, Howell, P. Lynne, Sheppard, Donald C.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645995/
https://ncbi.nlm.nih.gov/pubmed/26342082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.679050
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