Modification of Asparagine-Linked Glycan Density for the Design of Hepatitis B Virus Virus-Like Particles with Enhanced Immunogenicity

The small envelope proteins (HBsAgS) derived from hepatitis B virus (HBV) represent the antigenic components of the HBV vaccine and are platforms for the delivery of foreign antigenic sequences. To investigate structure-immunogenicity relationships for the design of improved immunization vectors, we...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Hyakumura, Michiko, Walsh, Renae, Thaysen-Andersen, Morten, Kingston, Natalie J., La, Mylinh, Lu, Louis, Lovrecz, George, Packer, Nicolle H., Locarnini, Stephen, Netter, Hans J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645671/
https://ncbi.nlm.nih.gov/pubmed/26339047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01123-15
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi