Immune Protection against Virus Challenge in Aging Mice Is Not Affected by Latent Herpesviral Infections

Latent herpesvirus infections alter immune homeostasis. To understand if this results in aging-related loss of immune protection against emerging infections, we challenged old mice carrying latent mouse cytomegalovirus (CMV), herpes simplex virus 1 (HSV-1), and/or murine gammaherpesvirus 68 (MHV-68)...

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Vydáno v:J Virol
Hlavní autoři: Marandu, Thomas F., Oduro, Jennifer D., Borkner, Lisa, Dekhtiarenko, Iryna, Uhrlaub, Jennifer L., Drabig, Anja, Kröger, Andrea, Nikolich-Zugich, Janko, Cicin-Sain, Luka
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645637/
https://ncbi.nlm.nih.gov/pubmed/26339051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01989-15
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