Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization

Many viruses affect or exploit the phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin (mTOR) pathway, a crucial prosurvival signaling cascade. We report that this pathway was strongly activated in cells upon infection with the Old World alphavirus Semliki Forest virus (SFV), even...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Thaa, Bastian, Biasiotto, Roberta, Eng, Kai, Neuvonen, Maarit, Götte, Benjamin, Rheinemann, Lara, Mutso, Margit, Utt, Age, Varghese, Finny, Balistreri, Giuseppe, Merits, Andres, Ahola, Tero, McInerney, Gerald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645633/
https://ncbi.nlm.nih.gov/pubmed/26339054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01579-15
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados