Probing the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter globiformis with Halide Ions

The catalytic reaction of copper amine oxidase proceeds through a ping-pong mechanism comprising two half-reactions. In the initial half-reaction, the substrate amine reduces the Tyr-derived cofactor, topa quinone (TPQ), to an aminoresorcinol form (TPQ(amr)) that is in equilibrium with a semiquinone...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Murakawa, Takeshi, Hamaguchi, Akio, Nakanishi, Shota, Kataoka, Misumi, Nakai, Tadashi, Kawano, Yoshiaki, Yamaguchi, Hiroshi, Hayashi, Hideyuki, Tanizawa, Katsuyuki, Okajima, Toshihide
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645623/
https://ncbi.nlm.nih.gov/pubmed/26269595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.662726
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