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Probing the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter globiformis with Halide Ions
The catalytic reaction of copper amine oxidase proceeds through a ping-pong mechanism comprising two half-reactions. In the initial half-reaction, the substrate amine reduces the Tyr-derived cofactor, topa quinone (TPQ), to an aminoresorcinol form (TPQ(amr)) that is in equilibrium with a semiquinone...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4645623/ https://ncbi.nlm.nih.gov/pubmed/26269595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.662726 |
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