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Complexes of the copper-containing amine oxidase from Arthrobacter globiformis with the inhibitors benzylhydrazine and tranylcypromine

Complexes of Arthrobacter globiformis amine oxidase (AGAO) with the inhibitors benzylhydrazine and tranylcypromine (an antidepressant drug) have been refined at 1.86 and 1.65 Å resolution, respectively. Both inhibitors form covalent adducts with the TPQ cofactor. A tyrosine residue, proposed to act...

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Detalhes bibliográficos
Main Authors: Langley, David B., Trambaiolo, Daniel M., Duff, Anthony P., Dooley, David M., Freeman, Hans C., Guss, J. Mitchell
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443983/
https://ncbi.nlm.nih.gov/pubmed/18607080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910801556X
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