Complexes of the copper-containing amine oxidase from Arthrobacter globiformis with the inhibitors benzylhydrazine and tranylcypromine

Complexes of Arthrobacter globiformis amine oxidase (AGAO) with the inhibitors benzylhydrazine and tranylcypromine (an antidepressant drug) have been refined at 1.86 and 1.65 Å resolution, respectively. Both inhibitors form covalent adducts with the TPQ cofactor. A tyrosine residue, proposed to act...

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Hauptverfasser: Langley, David B., Trambaiolo, Daniel M., Duff, Anthony P., Dooley, David M., Freeman, Hans C., Guss, J. Mitchell
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2008
Schlagworte:
Protein Structure Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443983/
https://ncbi.nlm.nih.gov/pubmed/18607080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910801556X
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