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Complexes of the copper-containing amine oxidase from Arthrobacter globiformis with the inhibitors benzylhydrazine and tranylcypromine

Complexes of Arthrobacter globiformis amine oxidase (AGAO) with the inhibitors benzylhydrazine and tranylcypromine (an antidepressant drug) have been refined at 1.86 and 1.65 Å resolution, respectively. Both inhibitors form covalent adducts with the TPQ cofactor. A tyrosine residue, proposed to act...

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Bibliografiske detaljer
Main Authors: Langley, David B., Trambaiolo, Daniel M., Duff, Anthony P., Dooley, David M., Freeman, Hans C., Guss, J. Mitchell
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443983/
https://ncbi.nlm.nih.gov/pubmed/18607080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910801556X
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