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Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): CLOSED AND OPEN STATE CHANNEL MODELS

The cystic fibrosis transmembrane conductance regulator (CFTR) is a member of the ATP-binding cassette (ABC) transporter superfamily. CFTR controls the flow of anions through the apical membrane of epithelia. Dysfunctional CFTR causes the common lethal genetic disease cystic fibrosis. Transitions be...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Corradi, Valentina, Vergani, Paola, Tieleman, D. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645605/
https://ncbi.nlm.nih.gov/pubmed/26229102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.665125
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