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Maternal Vaccination with a Fimbrial Tip Adhesin and Passive Protection of Neonatal Mice against Lethal Human Enterotoxigenic Escherichia coli Challenge

Globally, enterotoxigenic Escherichia coli (ETEC) is a leading cause of childhood and travelers' diarrhea, for which an effective vaccine is needed. Prevalent intestinal colonization factors (CFs) such as CFA/I fimbriae and heat-labile enterotoxin (LT) are important virulence factors and protec...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Luiz, Wilson B., Rodrigues, Juliana F., Crabb, Joseph H., Savarino, Stephen J., Ferreira, Luis C. S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645407/
https://ncbi.nlm.nih.gov/pubmed/26371126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00858-15
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