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Deficiencies in Cellular Processes Modulated by the Retinoblastoma Protein Do Not Account for Reduced Human Cytomegalovirus Replication in Its Absence

Despite encoding multiple viral proteins that modulate the retinoblastoma (Rb) protein in a manner classically defined as inactivation, human cytomegalovirus (HCMV) requires the presence of the Rb protein to replicate efficiently. In uninfected cells, Rb controls numerous pathways that the virus als...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: VanDeusen, Halena R., Kalejta, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645314/
https://ncbi.nlm.nih.gov/pubmed/26378180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01718-15
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