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The Retinoblastoma Tumor Suppressor Promotes Efficient Human Cytomegalovirus Lytic Replication

The retinoblastoma (Rb) tumor suppressor controls cell cycle, DNA damage, apoptotic, and metabolic pathways. DNA tumor virus oncoproteins reduce Rb function by either inducing Rb degradation or physically disrupting complexes between Rb and its myriad binding proteins. Human cytomegalovirus (HCMV),...

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Foilsithe in:J Virol
Main Authors: VanDeusen, Halena R., Kalejta, Robert F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403481/
https://ncbi.nlm.nih.gov/pubmed/25694602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00175-15
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