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Vpr Enhances Tumor Necrosis Factor Production by HIV-1-Infected T Cells

The HIV-1 accessory protein Vpr displays different activities potentially impacting viral replication, including the arrest of the cell cycle in the G(2) phase and the stimulation of apoptosis and DNA damage response pathways. Vpr also modulates cytokine production by infected cells, but this proper...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Roesch, Ferdinand, Richard, Léa, Rua, Réjane, Porrot, Françoise, Casartelli, Nicoletta, Schwartz, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645299/
https://ncbi.nlm.nih.gov/pubmed/26401039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02098-15
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