Phosphonate Pendant Armed Propylene Cross-Bridged Cyclam: Synthesis and Evaluation as a Chelator for Cu-64

[Image: see text] A propylene cross-bridged macrocyclic chelator with two phosphonate pendant arms (PCB-TE2P) was synthesized from cyclam. Various properties of the synthesized chelator, including Cu-complexation, Cu-complex stability, (64)Cu-radiolabeling, and in vivo behavior, were studied and com...

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Udgivet i:ACS Med Chem Lett
Main Authors: Bhatt, Nikunj, Soni, Nisarg, Ha, Yeong Su, Lee, Woonghee, Pandya, Darpan N., Sarkar, Swarbhanu, Kim, Jung Young, Lee, Hochun, Kim, Sun Hee, An, Gwang Il, Yoo, Jeongsoo
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2015
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645244/
https://ncbi.nlm.nih.gov/pubmed/26617972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00362
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