A Novel Side-Bridged Hybrid Phosphonate/Acetate Pendant Cyclam: Synthesis, Characterization, and (64)Cu Small Animal PET Imaging

Copper-64 (t(½) = 12.7 hr; β(+): 0.653 MeV, 17.4%; β(−): 0.578 MeV, 39%) is produced in a biomedical cyclotron and has applications in both imaging and therapy. Macrocyclic chelators are widely used as bifunctional chelators to bind copper radionuclides to antibodies and peptides owing to their rela...

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Detalhes bibliográficos
Main Authors: Boswell, C. Andrew, Regino, Celeste A. S., Baidoo, Kwamena E., Wong, Karen J., Milenic, Diane E., Kelley, James A., Lai, Christopher C., Brechbiel, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636550/
https://ncbi.nlm.nih.gov/pubmed/19101152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.11.073
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