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Molecular Pathways: Targeting Diacylglycerol Kinase Alpha in Cancer

Lipid kinases have largely been neglected as targets in cancer, and an increasing number of reports suggest diacylglycerol kinase alpha (DGKα) may be one with promising therapeutic potential. DGKα is one of ten DGK family members that convert diacylglycerol (DAG) to phosphatidic acid (PA), and both...

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Vydáno v:Clin Cancer Res
Hlavní autor: Purow, Benjamin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644682/
https://ncbi.nlm.nih.gov/pubmed/26420856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0413
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