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Modeling the complex pathology of Alzheimer’s disease in Drosophila

Alzheimer’s disease (AD) is the leading cause of dementia and the most common neurodegenerative disorder. AD is mostly a sporadic disorder and its main risk factor is age, but mutations in three genes that promote the accumulation of the amyloid-β (Aβ42) peptide revealed the critical role of Amyloid...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Fernandez-Funez, Pedro, de Mena, Lorena, Rincon-Limas, Diego E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644457/
https://ncbi.nlm.nih.gov/pubmed/26024860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.05.013
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