VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption

Vascular endothelial growth factor C (VEGF-C) binding to its tyrosine kinase receptor VEGFR-3 drives lymphatic vessel growth during development and in pathological processes. Although the VEGF-C/VEGFR-3 pathway provides a target for treatment of cancer and lymphedema, the physiological functions of...

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Bibliografiske detaljer
Udgivet i:EMBO Mol Med
Main Authors: Nurmi, Harri, Saharinen, Pipsa, Zarkada, Georgia, Zheng, Wei, Robciuc, Marius R, Alitalo, Kari
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
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Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644375/
https://ncbi.nlm.nih.gov/pubmed/26459520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505731
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