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Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner

INTRODUCTION: The endocannabinoid system modulates function of immune cells and mesenchymal cells such as fibroblasts, which contribute to cartilage destruction in rheumatoid arthritis (RA). The aim of the study was to determine the influence of N-acylethanolamines anandamide (AEA), palmitoylethanol...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Lowin, Torsten, Apitz, Martin, Anders, Sven, Straub, Rainer H.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644337/
https://ncbi.nlm.nih.gov/pubmed/26567045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0845-5
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