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A thyroid hormone network exists in synovial fibroblasts of rheumatoid arthritis and osteoarthritis patients

While patients with rheumatoid arthritis (RA) sometimes demonstrate thyroidal illness, the role of thyroid hormones in inflamed synovial tissue is unknown. This is relevant because thyroid hormones stimulate immunity, and local cells can regulate thyroid hormone levels by deiodinases (DIO). The stud...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pörings, Anna-Sophia, Lowin, Torsten, Dufner, Bianca, Grifka, Joachim, Straub, Rainer H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744488/
https://ncbi.nlm.nih.gov/pubmed/31519956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49743-4
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