The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression

Nuclear pore complexes (NPCs) influence gene expression besides their established function in nuclear transport. The TREX-2 complex localizes to the NPC basket and affects gene-NPC interactions, transcription, and mRNA export. How TREX-2 regulates the gene expression machinery is unknown. Here, we s...

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Udgivet i:Cell
Main Authors: Schneider, Maren, Hellerschmied, Doris, Schubert, Tobias, Amlacher, Stefan, Vinayachandran, Vinesh, Reja, Rohit, Pugh, B. Franklin, Clausen, Tim, Köhler, Alwin
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644235/
https://ncbi.nlm.nih.gov/pubmed/26317468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.07.059
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