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Monogenic forms of childhood obesity due to mutations in the leptin gene

Congenital leptin deficiency is a rare autosomal recessive monogenic obesity syndrome caused by mutations in the leptin gene. This review describes the molecular and cellular characteristics of the eight distinct mutations found so far in humans.

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Bibliografski detalji
Izdano u:Mol Cell Pediatr
Glavni autori: Funcke, Jan-Bernd, von Schnurbein, Julia, Lennerz, Belinda, Lahr, Georgia, Debatin, Klaus-Michael, Fischer-Posovszky, Pamela, Wabitsch, Martin
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644131/
https://ncbi.nlm.nih.gov/pubmed/26567097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40348-014-0003-1
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