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Monogenic forms of childhood obesity due to mutations in the leptin gene
Congenital leptin deficiency is a rare autosomal recessive monogenic obesity syndrome caused by mutations in the leptin gene. This review describes the molecular and cellular characteristics of the eight distinct mutations found so far in humans.
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| Publicado no: | Mol Cell Pediatr |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4644131/ https://ncbi.nlm.nih.gov/pubmed/26567097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40348-014-0003-1 |
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