In a Canine Pneumonia Model of Exchange-Transfusion, Altering the Age but Not the Volume of Older Red Blood Cells Markedly Alters Outcome

BACKGROUND: Massive exchange-transfusion of 42-day-old red blood cells (RBCs) in a canine model of S. aureus pneumonia resulted in in vivo hemolysis with increases in cell-free hemoglobin (CFH), transferrin bound iron (TBI), non-transferrin bound iron (NTBI), and mortality. We have previously shown...

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Pubblicato in:Transfusion
Autori principali: Cortés-Puch, Irene, Remy, Kenneth E., Solomon, Steven B., Sun, Junfeng, Wang, Dong, Al-Hamad, Mariam, Kelly, Seth M., Sinchar, Derek, Bellavia, Landon, Kanias, Tamir, Popovsky, Mark A., Kim-Shapiro, Daniel B., Klein, Harvey G., Natanson, Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644122/
https://ncbi.nlm.nih.gov/pubmed/26469998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.13275
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