Transfused Older Stored Red Blood Cells Improve the Clinical Course and Outcome in a Canine Lethal Hemorrhage/Reperfusion Model

BACKGROUND: In canine models, transfused older stored red blood cells (RBCs) hemolyze in vivo resulting in significantly increased intravascular cell free hemoglobin (CFH) and non-transferrin bound iron (NTBI). During canine bacterial pneumonia with septic shock, but not in controls, older stored RB...

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Publicat a:Transfusion
Autors principals: Solomon, Steven B., Cortés-Puch, Irene, Sun, Junfeng, Remy, Kenneth E., Wang, Dong, Feng, Jing, Khan, Sameena S., Sinchar, Derek, Kim-Shapiro, Daniel B., Klein, Harvey G., Natanson, Charles
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644126/
https://ncbi.nlm.nih.gov/pubmed/26175134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/trf.13213
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