Cis-regulatory mechanisms governing stem and progenitor cell transitions

Cis-element encyclopedias provide information on phenotypic diversity and disease mechanisms. Although cis-element polymorphisms and mutations are instructive, deciphering function remains challenging. Mutation of an intronic GATA motif (+9.5) in GATA2, encoding a master regulator of hematopoiesis,...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Johnson, Kirby D., Kong, Guangyao, Gao, Xin, Chang, Yuan-I, Hewitt, Kyle J., Sanalkumar, Rajendran, Prathibha, Rajalekshmi, Ranheim, Erik A., Dewey, Colin N., Zhang, Jing, Bresnick, Emery H.
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2015
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643771/
https://ncbi.nlm.nih.gov/pubmed/26601269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500503
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