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Integrative analysis with ChIP-seq advances the limits of transcript quantification from RNA-seq

RNA-seq is currently the technology of choice for global measurement of transcript abundances in cells. Despite its successes, isoform-level quantification remains difficult because short RNA-seq reads are often compatible with multiple alternatively spliced isoforms. Existing methods rely heavily o...

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Bibliografske podrobnosti
izdano v:Genome Res
Main Authors: Liu, Peng, Sanalkumar, Rajendran, Bresnick, Emery H., Keleş, Sündüz, Dewey, Colin N.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971760/
https://ncbi.nlm.nih.gov/pubmed/27405803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.199174.115
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