Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo

The generation of hematopoietic stem cells (HSCs) from hemogenic endothelium within the aorta, gonad, mesonephros (AGM) region of the mammalian embryo is crucial for development of the adult hematopoietic system. We described a deletion of a Gata2 cis-element (+9.5) that depletes fetal liver HSCs, i...

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Detaylı Bibliyografya
Asıl Yazarlar: Gao, Xin, Johnson, Kirby D., Chang, Yuan-I, Boyer, Meghan E., Dewey, Colin N., Zhang, Jing, Bresnick, Emery H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2013
Konular:
Brief Definitive Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865483/
https://ncbi.nlm.nih.gov/pubmed/24297994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130733
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