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Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo
The generation of hematopoietic stem cells (HSCs) from hemogenic endothelium within the aorta, gonad, mesonephros (AGM) region of the mammalian embryo is crucial for development of the adult hematopoietic system. We described a deletion of a Gata2 cis-element (+9.5) that depletes fetal liver HSCs, i...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3865483/ https://ncbi.nlm.nih.gov/pubmed/24297994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130733 |
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