Predicting Response to Histone Deacetylase Inhibitors Using High-Throughput Genomics

BACKGROUND: Many disparate biomarkers have been proposed as predictors of response to histone deacetylase inhibitors (HDI); however, all have failed when applied clinically. Rather than this being entirely an issue of reproducibility, response to the HDI vorinostat may be determined by the additive...

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Опубликовано в: :J Natl Cancer Inst
Главные авторы: Geeleher, Paul, Loboda, Andrey, Lenkala, Divya, Wang, Fan, LaCroix, Bonnie, Karovic, Sanja, Wang, Jacqueline, Nebozhyn, Michael, Chisamore, Michael, Hardwick, James, Maitland, Michael L., Huang, R. Stephanie
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643634/
https://ncbi.nlm.nih.gov/pubmed/26296641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv247
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