Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer

BACKGROUND: Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy, responsible for 13 000 deaths per year in the United States. Risk prediction based on identifying germline mutations in ovarian cancer susceptibility genes could have a clinically significant impact on reducing...

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Pubblicato in:J Natl Cancer Inst
Autori principali: Ramus, Susan J., Song, Honglin, Dicks, Ed, Tyrer, Jonathan P., Rosenthal, Adam N., Intermaggio, Maria P., Fraser, Lindsay, Gentry-Maharaj, Aleksandra, Hayward, Jane, Philpott, Susan, Anderson, Christopher, Edlund, Christopher K., Conti, David, Harrington, Patricia, Barrowdale, Daniel, Bowtell, David D., Alsop, Kathryn, Mitchell, Gillian, Cicek, Mine S., Cunningham, Julie M., Fridley, Brooke L., Alsop, Jennifer, Jimenez-Linan, Mercedes, Poblete, Samantha, Lele, Shashi, Sucheston-Campbell, Lara, Moysich, Kirsten B., Sieh, Weiva, McGuire, Valerie, Lester, Jenny, Bogdanova, Natalia, Dürst, Matthias, Hillemanns, Peter, Odunsi, Kunle, Whittemore, Alice S., Karlan, Beth Y, Dörk, Thilo, Goode, Ellen L., Menon, Usha, Jacobs, Ian J., Antoniou, Antonis C., Pharoah, Paul D. P., Gayther, Simon A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643629/
https://ncbi.nlm.nih.gov/pubmed/26315354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv214
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