Tagging Single Nucleotide Polymorphisms in the BRIP1 Gene and Susceptibility to Breast and Ovarian Cancer

BACKGROUND: BRIP1 interacts with BRCA1 and functions in regulating DNA double strand break repair pathways. Germline BRIP1 mutations are associated with breast cancer and Fanconi anemia. Thus, common variants in the BRIP1 are candidates for breast and ovarian cancer susceptibility. METHODS: We used...

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Hauptverfasser: Song, Honglin, Ramus, Susan J., Kjaer, Susanne Krüger, Hogdall, Estrid, DiCioccio, Richard A., Whittemore, Alice S., McGuire, Valerie, Hogdall, Claus, Jacobs, Ian J., Easton, Douglas F., Ponder, Bruce A.J., Dunning, Alison M., Gayther, Simon A., D.P. Pharoah, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800910/
https://ncbi.nlm.nih.gov/pubmed/17342202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000268
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