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Specific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa

STUDY QUESTION: Are significant abnormalities of CatSper function present in IVF patients with normal sperm concentration and motility and if so what is their functional significance for fertilization success? SUMMARY ANSWER: Sperm with a near absence of CatSper current failed to respond to activati...

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發表在:Hum Reprod
Main Authors: Williams, Hannah L., Mansell, Steven, Alasmari, Wardah, Brown, Sean G., Wilson, Stuart M., Sutton, Keith A., Miller, Melissa R., Lishko, Polina V., Barratt, Christopher L.R., Publicover, Steven J., Martins da Silva, Sarah
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643530/
https://ncbi.nlm.nih.gov/pubmed/26453676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dev243
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