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Specific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa

STUDY QUESTION: Are significant abnormalities of CatSper function present in IVF patients with normal sperm concentration and motility and if so what is their functional significance for fertilization success? SUMMARY ANSWER: Sperm with a near absence of CatSper current failed to respond to activati...

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Publicat a:Hum Reprod
Autors principals: Williams, Hannah L., Mansell, Steven, Alasmari, Wardah, Brown, Sean G., Wilson, Stuart M., Sutton, Keith A., Miller, Melissa R., Lishko, Polina V., Barratt, Christopher L.R., Publicover, Steven J., Martins da Silva, Sarah
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643530/
https://ncbi.nlm.nih.gov/pubmed/26453676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dev243
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