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Specific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa

STUDY QUESTION: Are significant abnormalities of CatSper function present in IVF patients with normal sperm concentration and motility and if so what is their functional significance for fertilization success? SUMMARY ANSWER: Sperm with a near absence of CatSper current failed to respond to activati...

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Detalhes bibliográficos
Publicado no:Hum Reprod
Main Authors: Williams, Hannah L., Mansell, Steven, Alasmari, Wardah, Brown, Sean G., Wilson, Stuart M., Sutton, Keith A., Miller, Melissa R., Lishko, Polina V., Barratt, Christopher L.R., Publicover, Steven J., Martins da Silva, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643530/
https://ncbi.nlm.nih.gov/pubmed/26453676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dev243
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