Activin A/BMP2 chimera AB235 drives efficient redifferentiation of long term cultured autologous chondrocytes

Autologous chondrocyte implantation (ACI) depends on the quality and quantity of implanted cells and is hindered by the fact that chondrocytes cultured for long periods of time undergo dedifferentiation. Here we have developed a reproducible and efficient chondrogenic protocol to redifferentiate cho...

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Udgivet i:Sci Rep
Main Authors: Jiménez, G., López-Ruiz, E., Kwiatkowski, W., Montañez, E., Arrebola, F., Carrillo, E., Gray, P. C., Belmonte, J. C. Izpisua, Choe, S., Perán, M., Marchal, J. A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643338/
https://ncbi.nlm.nih.gov/pubmed/26563344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16400
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