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An Activin A/BMP2 chimera displays bone healing properties superior to those of BMP2
Recombinant Bone Morphogenetic Protein 2 (rhBMP2) has been used clinically to treat bone fractures in human patients. However, the high doses of rhBMP2 required for a therapeutic response can cause undesirable side effects. Here, we demonstrate that a novel Activin A/BMP2 (AB2) chimera, AB204, promo...
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| Pubblicato in: | J Bone Miner Res |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4276739/ https://ncbi.nlm.nih.gov/pubmed/24692083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2238 |
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