טוען...
Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL, and results in arteriovenous malformations
Pericytes regulate vessel stability and pericyte dysfunction contributes to retinopathies, stroke, and cancer. Here we define Notch as a key regulator of pericyte function during angiogenesis. In Notch1(+/−); Notch3(−/−) mice, combined deficiency of Notch1 and Notch3 altered pericyte interaction wit...
שמור ב:
| הוצא לאור ב: | Sci Rep |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4643246/ https://ncbi.nlm.nih.gov/pubmed/26563570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16449 |
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